MARC details
000 -LEADER |
fixed length control field |
06260nam a2200709 i 4500 |
001 - CONTROL NUMBER |
control field |
9780750311342 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
IOP |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20190906144118.0 |
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
fixed length control field |
m eo d |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr cn |||m|||a |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
151001s2015 enka ob 000 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780750311342 |
Qualifying information |
ebook |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780750311366 |
Qualifying information |
mobi |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
Canceled/invalid ISBN |
9780750311359 |
Qualifying information |
print |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1088/978-0-7503-1134-2 |
Source of number or code |
doi |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(CaBNVSL)thg00931902 |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(OCoLC)922907770 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
CaBNVSL |
Language of cataloging |
eng |
Description conventions |
rda |
Transcribing agency |
CaBNVSL |
Modifying agency |
CaBNVSL |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC262 |
Item number |
.M547 2015eb |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PHVN |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI009000 |
Source |
bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
616.99/4 |
Edition number |
23 |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Mierk, Claudia Tanja, |
Relator term |
author. |
245 10 - TITLE STATEMENT |
Title |
Physics of cancer / |
Statement of responsibility, etc. |
Claudia Tanja Mierk. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : |
Name of producer, publisher, distributor, manufacturer |
IOP Publishing, |
Date of production, publication, distribution, manufacture, or copyright notice |
[2015] |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 online resource (various pagings) : |
Other physical details |
illustrations (some color). |
336 ## - CONTENT TYPE |
Content type term |
text |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
electronic |
Source |
isbdmedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Source |
rdacarrier |
490 1# - SERIES STATEMENT |
Series statement |
[IOP release 2] |
490 1# - SERIES STATEMENT |
Series statement |
IOP expanding physics, |
International Standard Serial Number |
2053-2563 |
500 ## - GENERAL NOTE |
General note |
"Version: 20150901"--Title page verso. |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc |
Includes bibliographical references. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Preface -- About the author -- Introduction -- part 1. Introduction to tumor biology from a biophysical point of view -- 1. Initiation of a neoplasm or tumor -- 1.1. Initiation of a neoplasm, tumor growth and neoangiogenesis -- 1.2. Malignant progression of cancer (metastasis) -- 1.3. Hallmarks of cancer -- 1.4. The impact of the mechanical properties of cancer cells on their migration |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
2. Inflammation and cancer -- 2.1. Inflammation : acute and chronic -- 2.2. The dual relationship between inflammation and cancer |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
part 2. The role of the mechanical properties of cancer cells in cellular invasion -- 3. Cellular stiffness and deformability -- 3.1. Magnetic tweezers -- 3.2. Optical cell stretcher |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
4. Cell-cell and cell-matrix adhesion strength, local cell stiffness and forces -- 4.1. Atomic force microscopy -- 4.2. Traction forces |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
5. Cytoskeletal remodeling dynamics -- 5.1. Nano-scale particle tracking -- 5.2. FRAP |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
6. Intermediate filaments and nuclear deformability during matrix invasion -- 6.1. Intermediate filaments, cellular mechanical properties and cellular motility -- 6.2. The role of intermediate and actin filaments interactions -- 6.3. The role of nuclear intermediate filaments in cell invasion -- 6.4. The role of cell division in cellular motility |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
7. Cell surface tension, the mobility of cell surface receptors and their location in specific regions -- 7.1. Surface tension -- 7.2. The mobility of surface receptors -- 7.3. Specific membrane regions as a location for surface receptors |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
part 3. The impact of the tumor microenvironment on cellular invasion -- 8. The mechanical and structural properties of the microenvironment -- 8.1. Pore size -- 8.2. Matrix stiffness -- 8.3. Matrix composition -- 8.4. The impact of fiber thickness, connection points and polymerization dynamics on cancer cell invasion -- 8.5. The role of a matrix stiffness gradient in cancer cell invasion |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
9. The impact of cells and substances within the extracellular matrix tissue on mechanical properties and cell invasion -- 9.1. The impact of tumor-associated fibroblasts on matrix mechanical properties -- 9.2. The role of substances and growth factors within the extracellular matrix in cancer cell's mechanical properties |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
part 4. The impact of the mechanical and biochemical interaction of cancer cells with other cells in transendothelial migration -- 10. The role of endothelial cell-cell adhesions -- 10.1. The expression of cell-cell adhesion molecules -- 10.2. The strength of cell-cell adhesions -- 10.3. The cancer cell transmigration route -- 10.4. The role of cancer cell exerted invadopodia during transendothelial migration |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
11. The mechanical properties of endothelial cells altered by aggressive cancer cells -- 11.1. The role of endothelial cell stiffness -- 11.2. The role of the endothelial contractile apparatus -- 12. The role of macrophages during cancer cell transendothelial migration. |
520 3# - SUMMARY, ETC. |
Summary, etc. |
Physics of Cancer focuses on the mechanical properties of cancer cells and their role in cancer disease and metastasis. It discusses the role of the mechanical properties of interacting cells and the connective tissue microenvironment and describes the role of an inflammation during cancer disease. This outstanding book is the first to describe cancer disease from a biophysical point of view without being incomplete in describing the biological site of cancer. Originating in part from the author's own courses on tumor biology and cellular biophysics, this book is suitable for both students and researchers in this dynamic interdisciplinary field, be they from a physical, biological or medical sciences background. |
521 ## - TARGET AUDIENCE NOTE |
Target audience note |
Graduate students and active researchers in biophysics, medical physics, oncology, cell biology, medicine and pharmacology. |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Also available in print. |
538 ## - SYSTEM DETAILS NOTE |
System details note |
Mode of access: World Wide Web. |
538 ## - SYSTEM DETAILS NOTE |
System details note |
System requirements: Adobe Acrobat Reader. |
545 ## - BIOGRAPHICAL OR HISTORICAL DATA |
Biographical or historical data |
Claudia Tanja Mierke has a background in biology and molecular oncology and is Head of the Biological Physics Division at the University of Leipzig where she regularly teaches molecular and cell biology, biophysics and soft matter physics to physicists. She is concerned with various research areas developing our understanding of the physical aspects of cancer. |
588 0# - SOURCE OF DESCRIPTION NOTE |
Source of description note |
Title from PDF title page (viewed on October 1, 2015). |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Biophysics. |
Source of heading or term |
bicssc |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
SCIENCE / Life Sciences / Biophysics. |
Source of heading or term |
bisacsh |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Cancer. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Biophysics. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Pathology, Molecular. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
Institute of Physics (Great Britain), |
Relator term |
publisher. |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Print version: |
International Standard Book Number |
9780750311359 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
IOP expanding physics. |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
IOP (Series). |
Name of part/section of a work |
Release 2. |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="https://iopscience.iop.org/book/978-0-7503-1134-2">https://iopscience.iop.org/book/978-0-7503-1134-2</a> |