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Biofilm associated antimicrobial resistance and its recovery edited by Dibyajit Lahiri...[et.al.,]

By: Contributor(s): Material type: TextTextPublication details: Boca Raton CRC Press 2024Description: 264pISBN:
  • 9781032250335
Subject(s): DDC classification:
  • 579.17 LAH-D
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Holdings
Item type Current library Collection Shelving location Call number Copy number Status Notes Date due Barcode Item holds
New books on display New books on display BITS Pilani Hyderabad 570 New Book Display (Welcome to Reserve) 579.17 LAH-D (Browse shelf(Opens below)) GBP 115.00 Available Display-07 49661
Total holds: 0

"A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance. Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues. The book titled "Biofilm Associated on Antimicrobial Resistance and Its Recovery" provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research. Features: A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistance. Recent research in the development of antibiofilm remedies involving biogenic compounds. Advancements in the biofilm detection methodologies with the cutting-edge technologies. This book serves as a reference book for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology

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