000			01525nam a22001937a 4500
008			151222b2014 xxu||||| |||| 00| 0 eng d
020			_a9780815342441
082			_a571.74 LIM-W
100			_aLim, Wendell.
245			_aCell signaling : _bprinciples and mechanisms / _cWendell Lim, Bruce Mayer and Tony Pawson
260			_aNew York _bGarland Science _c2014
300			_a400 p.
365			_aGBP _b59.00
500			_a"Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods"--
650			_aCell interaction
650			_aCellular signal transduction
700			_aMayer, Bruce., jt. auth.
700			_aPawson, Tony., jt. auth.
999			_c22328 _d22328