000			01889nam a22001697a 4500
999			_c65616 _d65616
008			200611b2018 ||||| |||| 00| 0 eng d
020			_a9781107052734
082			_a571.6 SHE-M
100			_aSheetz, Michael
245			_aCell as a machine / _cMichael Sheetz and Hanry Yu
260			_aIndia _bCambridge University Press _c2018
300			_a418 p.
365			_aGBP _b69.99.
500			_aThis unique introductory text explains cell functions using the engineering principles of robust devices. Adopting a process-based approach to understanding cell and tissue biology, it describes the molecular and mechanical features that enable the cell to be robust in operating its various components, and explores the ways in which molecular modules respond to environmental signals to execute complex functions. The design and operation of a variety of complex functions are covered, including engineering lipid bilayers to provide fluid boundaries and mechanical controls, adjusting cell shape and forces with dynamic filament networks, and DNA packaging for information retrieval and propagation. Numerous problems, case studies and application examples help readers connect theory with practice, and solutions for instructors and videos of lectures accompany the book online. Assuming only basic mathematical knowledge, this is an invaluable resource for graduate and senior undergraduate students taking single-semester courses in cell mechanics, biophysics and cell biology. Uniquely links together the biology, biophysics, and engineering principles underlying cell functions Avoids complex mathematical treatments, making it accessible to students with only a basic mathematical background Additional information about many of the functions described in the book can be found online at www.mechanobio.info
650			_aCell physiology
650			_aCells--Mechanical properties