000			01809nam a22001937a 4500
008			210727b2017 ||||| |||| 00| 0 eng d
020			_a9780128053881
082			_a572.865 TOL-T
100			_aTollefsbol, Trygve O
245			_aHandbook of epigenetics : _bthe new molecular and medical genetics / _cTrygve O Tollefsbol
250			_a2nd ed.
260			_aUnited Kingdom _bElsevier _c2017
300			_a668 p.
365			_aUSD _b200.00.
500			_aHandbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.
650			_aEpigenetics
650			_aGenetic regulation
650			_aEpigenesis
999			_c66952 _d66952