000 01340nam a22001697a 4500
008 210806b1993 ||||| |||| 00| 0 eng d
020 _a9788126579570
082 _a615.1901 KUB-H
100 _aKubinyi, Hugo
245 _aQSAR :
_bHansch analysis and related approaches /
_cHugo Kubinyi
260 _aNew York
_bJohn Wiley
_c1993
300 _a240 p.
365 _aINR
_b3495.00.
500 _aFinding the new remedy for a certain disease: an inspired goal. QSAR, an invaluable tool in drug design, aids scientists to attain this aim. This book is a long-awaited comprehensive text to QSAR and related approaches. It provides a practice-oriented introduction to the theory, methods and analyses for QSAR relationships, including modelling-based and 3D approaches. Hugo Kubinyi is a leading expert in QSAR. Readers will benefit from the author's 20 years of practical experience, from his careful calculations and recalculations of thousands of QSAR equations. Among the topics covered are: - physicochemical parameters - quantitative models - statistical methods - Hansch analysis - Free Wilson analysis - 3D-QSAR approaches The book can readily be used as a textbook due to its high didactic value and numerous examples (over 200 equations and 1100 references).
650 _aPharmaceutical chemistry
650 _aQSAR (Biochemistry)
999 _c67057
_d67057