000			02546nam a22001937a 4500
008			210907b2020 |||||||| |||| 00| 0 eng d
020			_a9789389354720
082			_a616.462 VEE-C
100			_aVeeresham, Ciddi
245			_aPhytochemicals for diabetic complications / _cCiddi Veeresham and Ajmera Rama Rao
260			_aIndia _bPharmaMed Press _c2020
300			_a146 p.
365			_aINR _b995.00.
500			_aDiabetes Mellitus (DM) is a chronic metabolic disorder of impaired metabolism of Carbohydrates fats and proteins, characterized by hyperglycemia resulting from decreased utilization of carbohydrates and excessive glycogenolysis and Gluconeogenesis from amino acids and fatty acids. People with Diabetes mellitus are at higher risks of developing serous diabetic complications such as neuropathy, nephropathy, cataract and heart attacks. Four molecular mechanisms are involved in the development of diabetic complications; increase in the flux of glucose through the polyol pathway, increased intracellular formation of advanced glycation end products (AGES), activation of protein kinase C (PKC) and increased flux through the hexosamine pathway. Among these, the polyol pathway plays a vital role in the development of diabetic complications. In view of the researchers started working on synthetic compounds for the treatment of diabetic complications. The failure of synthetic compounds because of their low safety and poor pharmacokinetics made look into the alternative source from plants/phytochemicals. So in view of these, the book gives details about several plants and phytochemicals reported for the treatment of diabetic complications. The book will be valuable for people who work as plants/ phytochemicals for the treatment of diabetic complications. This book will also be useful for the students, researchers and teachers in the subjects of Pharmacognosy, Botany, Pharmacy, Ayurveda and other Allied Life Sciences. Provides screening methods for Aldose reductase enzyme, AGEs involved in the diabetic complications. Provides a piece of comprehensive information as plants & phytochemicals reported for diabetic complications. It gives herbal medicine and nutraceuticals used in the treatment of diabetic complications. Ciddi Veeresham has 30 years of experience in teaching and research on Pharmacognosy and pharmacy. He supervised 28 Ph. Ds and published 150 research papers
650			_aDiabetic complications
650			_aHerbal medicine
650			_aPhyto constituents
700			_aRao, Ajmera Rama
999			_c67289 _d67289