000			02591nam a2200229 4500
008			230912b2010 |||||||| |||| 00| 0 eng d
020			_a9781420094541
082			_a571.634 CHA-A
100			_aChauviere, Arnaud
245			_aCell mechanics : _bfrom single scale-based models to multiscale modeling edited by _cArnaud Chauviere, Luigi Preziosi and Claude Verdier
260			_aBoca Raton _bCRC Press _c2010
300			_a456p.
365			_aGBP _b170.00
440			_aChapman & Hall/CRC Mathematical & Computational Biology _v32
500			_aUbiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. This book discusses the tool of micro rheology for investigating cell mechanical properties, and Multiphysics and multiscale approaches for studying intracellular mechanisms in cell motility. Ubiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling brings together new insight and research on mechanical, mathematical, physical, and biological approaches for simulating the behavior of cells, specifically tumor cells. In the first part of the text, the book discusses the powerful tool of microrheology for investigating cell mechanical properties, multiphysics and multiscale approaches for studying intracellular mechanisms in cell motility, and the role of subcellular effects involving certain genes for inducing cell motility in cancer. Focusing on models based on physical, mathematical, and computational approaches, the second section develops tools for describing the complex interplay of cell adhesion molecules and the dynamic evolution of the cell cytoskeleton. The third part explores cell interactions with the environment, particularly the role of external mechanical forces and their effects on cell behavior. The final part presents innovative models of multicellular systems for developmental biology, cancer, and embryogenesis. This book collects novel methods to apply to cells and tissues through a multiscale approach. It presents numerous existing tools while stimulating the discovery of new approaches that can lead to more effective and accurate predictions of pathologies.
650			_aTumors--Growth--Computer simulation
650			_aTumors--Growth--Mathematical models
650			_aCells--Mechanical properties
700			_aPreziosi, Luigi
700			_aVerdier, Claude
942			_2ddc
999			_c90831 _d90831