000			02005cam a2200301 a 4500
001			1651809
005			20241107163348.0
008			970207s1997 flua b 001 0 eng
010			_a 97007644
020			_a0849391423 (alk. paper)
020			_a9780849391422
050	0	0	_aQP551 _b.L56 1997
082	0	0	_a547.75 LLO-P _221
100	2		_aLloyd-Williams, Paul.
245	1	0	_aChemical approaches to the synthesis of peptides and proteins / _cPaul Lloyd-Williams, Fernando Albericio and Ernest Giralt.
260			_aBoca Raton _bCRC Press _c1997
300			_a278 p.
440		0	_aNew directions in organic and biological chemistry
500			_aOrganic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.
650		0	_aPeptides _xSynthesis.
650		0	_aProteins _xSynthesis.
700	1		_aAlbericio, Fernando.
700	1		_aGiralt, Ernest.
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0743/97007644-d.html
906			_a7 _bcbc _corignew _d1 _eocip _f19 _gy-gencatlg
942			_2ddc
955			_apc03 to ja00 02-07-97; jc09 02-10-97; jc02 to technician 02-10-97; jc13 02-10-97; CIP ver. pv08 06-23-97
999			_c92610 _d92610