000			01485nam a22001817a 4500
005			20250305111317.0
008			250305b2022 |||||||| |||| 00| 0 eng d
020			_a9781032041681
082			_a615.19 LI-J
100			_aLi, Jie Jack
245			_aDrug discovery with privileged building blocks : _btactics in medicinal chemistry / _cJie Jack Li and Minmin Yang
260			_aBoca Raton _bCRC Press _c2022
300			_a306p.
500			_aDrug Discovery with Privileged Building Blocks traces back PharmaBlockʹs founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to molecules' biological activities but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and regular analysis of new building block structures in the latest researches has proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book. Each chapter may be read and studied without learning the previous chapters. This book will be a good starting point for novice medicinal chemists and veteran medicinal chemists find it useful as well
650			_aPharmaceutical chemistry.
650			_aDrugs--Design.
650			_aDrug development.
999			_c93221 _d93221